ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the effects of sandblasting and different orthodontic adhesives on shear bond strength between zirconia and enamel.</p><p><b>METHODS</b>Zirconia ceramic samples were designed and manufactured for 40 extracted human maxillary first premolars with CAD/CAM system. The samples were randomized into 4 groups for surface treatment with sandblasting and non-treated with adhesives of 3M Transbond XT or Jingjin dental enamel bonding resin. After 24 h of bonded fixation, the shear bond strengths were measured by universal mechanical testing machine and analyzed with factorial variance analysis.</p><p><b>RESULTS</b>The shear bond strength was significantly higher in sandblasting group than in untreated group (P<0.05) and comparable between the two groups with the adhesives of Transbond XT and dental enamel bonding resin (P>0.05).</p><p><b>CONCLUSION</b>The shear bond strength between zirconia and enamel is sufficient after sandblasting regardless of the application of either adhesive.</p>